This article waslast modified on 10 July 2017.
Primary biliary cirrhosis is an autoimmune disorder that causes inflammation and scarring of the bile ducts inside the liver, causing continual liver damage and blockage of the bile flow. It is found most frequently in women between the ages of 35 and 60. More than 90% of those affected by primary biliary cirrhosis will have high levels of antimitochondrial antibodies.