This article waslast modified on 10 July 2017.
Hardening of tissue resulting from the formation of calcium salts within it; the abnormal hardening (calcinosis) leads to impaired organ function (e.g., in the kidneys or arteries). The process can result from a disturbance in the normal balance of hormones, vitamin D, and calcium and other minerals in the body. Calcification can also occur at the site of growth of a tumour, and its pattern can help to identify cancer during breast screening.