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There are many causes of peripheral neuropathy and in about 30% of cases; the cause is unknown and referred to as idiopathic neuropathy. Common causes include:

  • Diabetes – The longer the duration of diabetes, the greater the chance of developing neuropathy. It is estimated that half of all people who have been living with diabetes for 25 years or more have diabetic neuropathy.
  • Vitamin deficiencies – especially vitamin B12, but also other B vitamins such as B1, B6, B3, and vitamin E
  • Alcoholism – due to nutritional deficiencies and many think as a direct effect of the alcohol
  • Trauma – physical injury to a nerve; may be seen with repetitive stress and with any condition that traps, compresses, or damages a nerve (e.g., carpal tunnel syndrome).

Other causes include:

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