Conn's Syndrome

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The goal of treatment of Conn’s syndrome is to lower blood pressure to normal or near normal levels, decrease blood aldosterone levels, and resolve any electrolyte imbalance. The treatment used will depend on the cause of the excess aldosterone production. If it is due to a single benign adrenal tumour (Conn's syndrome), then the affected gland may be surgically removed. In many cases, this operation will remove the hypertension and other symptoms, but in other cases further treatment will be necessary to control blood pressure. If the primary hyperaldosteronism is due to a cancerous tumour (rare), then organs next to the adrenal gland will need to be looked at during surgery and may need to be removed.

If the cause of the primary hyperaldosteronism cannot be discovered (idiopathic) or appears to be due to hyperplasia in both adrenals, then surgery is not usually recommended. The patient’s condition will be treated with spironolactone (which blocks the action of aldosterone) and one or more blood pressure drug therapies.

Patients should consult with their doctors and, when necessary, with an endocrinologist (a specialist in the endocrine system).

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