Coeliac Disease Tests

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Formal name: Gluten-Sensitive Enteropathy Tests
Related tests: FBC, ESR, CRP, Calcium, Total Protein, Albumin, Vitamin D, Vitamin B12, Vitamin E, Iron, Folate, Total IgA, Anti-Endomysial Antibodies (EMA), Anti-tissue Transglutaminase Antibody (TTG), Deamidated gliadin peptide (DGP) antibodies, endoscopic intestinal biopsy

At a Glance

Why Get Tested?

  • To help in making a diagnosis of coeliac disease
  • Monitoring diagnosed patients to assess the effectiveness and degree of adherence to a gluten-free diet.
  • To exclude coeliac disease as a cause or association in some other diseases.

When to Get Tested?

There are different categories of patients who may get tested.

1. Patients who have symptoms suggestive of coeliac disease should be tested. These symptoms may include, for example:

  • chronic diarrhoea
  • abdominal pain
  • weight loss
  • anaemia
  • poor growth or chronic irritability in an infant or child

2. Patients with known coeliac disease may be tested by their doctor to help assess the effectiveness and observance of a gluten-free diet.
3. Patients with type 1 diabetes mellitus and autoimmune thyroid disease at diagnosis.
4. First degree relatives of people with coeliac disease.
5. Patients with metabolic bone disorder (e.g., osteoporosis), reproductive health problems and unexplained neurological symptoms.

Sample Required?

A blood sample taken from a vein in your arm

Test Preparation Needed?

Follow your doctor's instructions. For diagnosis, ingestion of gluten-containing foods for a time period, such as several weeks, is necessary. The test is accurate only if a gluten-containing diet is eaten during the testing process. If the patient is following a normal diet (containing gluten) it is advisable to eat some gluten in more than 1 meal every day for at least 6 weeks before testing.

For monitoring, no preparation is necessary.