Apolipoprotein E (Apo E) Genotyping

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Also known as: APOE Cardiac Risk
Formal name: Apolipoprotein E Genotyping

At a Glance

Why Get Tested?

To help confirm a diagnosis of Type III hyperlipoproteinaemia (also known as dysbetalipoproteinaemia, remnant disease or broad beta disease) and to evaluate a possible genetic cause of atherosclerosis. Outside of routine clinic practice e.g. for research purposes, it can be used to help confirm a diagnosis of late onset Alzheimer’s Disease (AD) in a symptomatic adult

When to Get Tested?

This is a non-standard test currently limited mostly to hospital specialists. It can be measured if your doctor suspects that your high cholesterol and triglyceride concentrations may be due to a genetically inherited disorder, or if you have specific types of xanthomas (yellowish raised patches) on your skin (particularly palms, knees and elbows).

Sample Required?

A blood sample taken from a vein in your arm

Test Preparation Needed?

None; however this test is often requested at the same time as other tests that require fasting (water only), so you may be instructed to fast for 12 hours prior to having this test.